Tuesday, January 29, 2013

Medications for heartburn cause HIV-infected bone fragility

      Normalize stomach acid drugs - proton pump inhibitors (PPIs) such as Prilosec (PRILOSEC, the active ingredient omeprazole) and Nexium (Nexium, the active ingredient esomeprazole), increase the risk of bone fractures in HIV-infected patients. This conclusion was made by researchers from Yale University based on the examination of more than forty thousand HIV-infected men of middle age.

     As reported by the speaker, (Julie Womack), those who regularly took PPIs, on average twice as often broken limbs, than those who did not take the drugs. The study authors suggest that the mechanism of action of PPIs with locking parientalnyh cells of the gastric mucosa, prevents bone regeneration processes and thus causes brittle bones.

No comments: